From some recent spam (my comments in italics):

"Please only reply to the email links in the text below.
Why can't you put the proper reply-to address in your email - or is that too difficult to set up?

"Are you looking to improve your website performance? Yes, then please take a moment to read this email.
If I was, you'd be the last person I'd ask.

"We can offer you a free website performance review, all that we ask in return is that you consider using our very competitively priced services to make the relevant improvements.
I can offer you free advice on how not to p*ss people off by offering them services they can do themselves, as would be perfectly obvious if you looked at the web site rather than buying a mailing list
 
"If you are interested please email us at ukbestwebsite-designing@lycos.com to request our free review form.
Hmm: web designers that can't afford their own mail domain and use a free service.

 

"Our work is always our best advert, so please email us at ukbestwebsite-designing@lycos.com if you want to see our design portfolio.
And they don't have their own web site to advertise a portfolio either?
 
"Thank you for taking the time to read this email. We look forward to working with you.
Dream on, Buster.
 
"If don't want to receive email from us, we apologise for any inconvenience caused and ask that you simply email ukbestwebsite-designing@lycos.com putting remove as the subject."
Too late: this is the third copy I have had and you have already really annoyed me. The last thing I shall do is to confirm that you have a genuine email adress, silly persons.